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Superbug Survives Radiation, Eats Toxic
Waste
DOE Microbial Genome Program Report A can of spoiled meat and nuclear waste may appear to have little in common, but the bacterium Deinococcus radiodurans thrives in both environments. This bacterium was discovered in 1956 when it was identified as the culprit in a can of spoiled ground beef thought to be radiation ”sterilized.” Scientists subsequently learned that its extreme radiation resistance enables the microbe to survive doses thousands of times higher than would kill most organisms, including humans. The remarkable DNA-repair processes of D. radiodurans allow it to stitch together flawlessly its own radiation-shattered genome in about 24 hours.
DOE chose this organism for DNA sequencing because of
its potential usefulness in cleaning up waste sites
containing radiation and toxic chemicals. Its DNA
sequence was completely determined in 1999, and
scientists now are exploring ways to add genes from
other organisms to expand D. radiodurans’
capabilities for removing toxic wastes from
contaminated sites. The added genes encode proteins
that transform heavy metals to a more benign biomass
and allow the concentration of heavy metals and the
breakdown of organic solvents such as toluene. Studies
into this organism’s remarkable DNA-repair
pathways also may help scientists better understand how
defects in human cellular processes might lead to the
development of cancers. |
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Last modified: Friday, September 23, 2005
Base URL: microbialgenomics.energy.gov
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